DOXEPIN HYDROCHLORIDECGT designated
FDA Orange Book ingredient view

What this means

DOXEPIN HYDROCHLORIDE is the active ingredient in DOXEPIN HYDROCHLORIDE / SINEQUAN / ZONALON and 1 others (marketed by NEW RIVER PHARMACEUTICALS INC and 3 others). Available as capsule;oral, concentrate;oral, and 2 other dosage forms. First approved 1981 — 44 years on market. Currently protected by 16 patents. The earliest market opportunity is 2027-05-17 (in 10 months). This drug has FDA Competitive Generic Therapy designation — first-to-file generic earns 180-day exclusivity, FDA expedites approval. 163+ ANDAs already filed — saturated market, thin margins expected. Bottom line: saturated — high competition will compress margins.

NDA products16
ANDA generics filed163
Blocking patents16
Exclusivities0
FDA Competitive Generic Therapy
Inadequate generic competition — first-to-file ANDA earns 180-day exclusivity

Designated 2022-04-19. First CGT approval: Edenbridge Pharmaceuticals, LLC, ANDA 213796, approved 2022-04-19

Blocking patents
16 patents associated
PatentTypeExpiryVerdict
US 9486437US 9486437U-6202027-05-17
US 9861607US 9861607U-6202027-05-17
US 10238620US 10238620U-6202027-05-17
US 12083090US 12083090U-6202027-05-17
US 10653662US 10653662U-6202027-05-17
US 9572814US 9572814U-6202027-07-19
US 10653660US 10653660U-6202027-07-19
US 11110074US 11110074U-6202027-07-19
US 7915307US 7915307U-6202027-08-23
US 11234954US 11234954U-6202028-01-17
US 10548871US 10548871U-6202028-04-10
US 11096920US 11096920U-6202028-04-10
US 9907780US 9907780Product2028-04-10
US 9107898US 9107898U-6202028-04-30
US 9532971US 9532971Product2029-05-31
US 8513299US 8513299U-6202030-09-06
NDA products
16 approved

EQ 10MG BASE · CAPSULE;ORAL · approved 1981-12-31 · NEW RIVER PHARMACEUTICALS INC

EQ 25MG BASE · CAPSULE;ORAL · approved 1981-12-31 · NEW RIVER PHARMACEUTICALS INC

EQ 50MG BASE · CAPSULE;ORAL · approved 1981-12-31 · NEW RIVER PHARMACEUTICALS INC

EQ 75MG BASE · CAPSULE;ORAL · approved 1981-12-31 · NEW RIVER PHARMACEUTICALS INC

EQ 100MG BASE · CAPSULE;ORAL · approved 1981-12-31 · NEW RIVER PHARMACEUTICALS INC

EQ 150MG BASE · CAPSULE;ORAL · approved 1987-04-12 · NEW RIVER PHARMACEUTICALS INC

SINEQUANNDA 016798

EQ 10MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons** · CAPSULE;ORAL · approved 1981-12-31 · PFIZER LABORATORIES DIV PFIZER INC

SINEQUANNDA 016798

EQ 25MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons** · CAPSULE;ORAL · approved 1981-12-31 · PFIZER LABORATORIES DIV PFIZER INC

SINEQUANNDA 016798

EQ 50MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons** · CAPSULE;ORAL · approved 1981-12-31 · PFIZER LABORATORIES DIV PFIZER INC

SINEQUANNDA 016798

EQ 75MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons** · CAPSULE;ORAL · approved 1981-12-31 · PFIZER LABORATORIES DIV PFIZER INC

ANDA generics
163 filed

EQ 150MG BASE · approved 2022-04-18

EQ 10MG BASE · approved 2020-07-27

EQ 25MG BASE · approved 2020-07-27

EQ 50MG BASE · approved 2020-07-27

EQ 75MG BASE · approved 2020-07-27

EQ 100MG BASE · approved 2020-07-27

EQ 10MG BASE · approved 2019-09-12

EQ 25MG BASE · approved 2019-09-12

EQ 50MG BASE · approved 2019-09-12

EQ 75MG BASE · approved 2019-09-12

+ 153 more ANDAs